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- Manjistha formula for lymph, skin and liver
Manjistha formula for lymph, skin and liver
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Organic Manjistha, Kalmegh and Guduchi in 96 vegetable capsules, in biodegradable bag.
Doseage: Take two capsules after a meal, once or twice a day.
Kalmegh
Kalmegh is helpful to cleanse the liver and in cases of cirrhosis of the liver. Kalmegh is helpful to cleanse the liver and in cases of cirrhosis of the liver. “The results of our study suggest that Kalmegh extract protects alcohol-induced toxic-effect in liver tissue.” http://www.ncbi.nlm.nih.gov/pubmed/6672491
The study indicates that the regenerative capability elicited by kalmegh is possibly due to its ability to reactivate liver function enzymes that catalyze the reaction of several biochemical and synthetic processes and that it may be useful for severe liver damage conditions. http://www.ncbi.nlm.nih.gov/pubmed/19679627
“Oral administration of a single dose of kalmegh leaf extract to adult male albino rats produced a dose-related and time-dependent characteristic activation of brush-border membrane-bound hydrolases, viz. lactase, maltase and sucrase in three regions of small intestine… Maximum stimulation of lactase and maltase was noted after 30 consecutive days of treatment while sucrase exhibited maximum activation after 15 consecutive of treatment with either KE or A. These results suggest that both KE and A accelerate intestinal digestion and absorption of carbohydrate by activating these intestinal disaccharidases. http://www.ncbi.nlm.nih.gov/pubmed/3938507
Guduchi "treatment effectively increased the intestinal absorption and retaining power of liver that regulated alcohol-induced multivitamin deficiency." Protective Effects of Tinospora cordifolia on Hepatic and Gastrointestinal Toxicity Induced by Chronic and Moderate Alcoholism
https://academic.oup.com/alcalc/article/51/1/1/2888192
Manjistha is an Ayurvedic plant renowned for its ability to bring health to the skin, particularly when pitta or kapha excesses may be present. It will leave the complexion bright, glowing, and radiating health from the inside-out. It is veryhelpful to relieve lymphatic congestion.
It can correct imbalances in the menstrual cycle. It helps balance excess kapha congestion and occasional discomfort, as well as excess heat and irritation from pitta, while helping to promote a healthy flow. When there may be kapha congestion and occasional discomfort in the cycle, manjistha mixed with shatavari can help soothe and correct the imbalance. It has been used traditionally by Ayurvedic practitioners to help support healthy pregnancies (please consult your Ayurvedic physician if you’re interested in learning more about this). It is definitely indicated when there is excess pitta in the mind and emotions. Thanks to its cooling effect, it can calm down heated emotions. Western research of this ancient Ayurvedic plant medicine:
This study finds a favorable comparison with milk thistle and manjistha in protecting the liver. https://www.ncbi.nlm.nih.gov/pubmed/16213120
This study examines The protective effect of Rubia cordifolia against lead nitrate-induced immune response impairment and kidney oxidative damage. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153710/
This study shows that a tincture will reduce the blood sugar level. Effect of alcoholic extract was also investigated on cold restraint induced stress and on memory impairment. Alcoholic extract enhanced brain gamma-amino-n-butyric acid (GABA) levels and decreased brain dopamine and plasma corticosterone levels. Acidity and ulcers caused due to cold restraint stress were inhibited by alcoholic extract. https://www.ncbi.nlm.nih.gov/pubmed/17176672
Other references involving Manjistha:
2009 Oriental Pharmacy and Experimental Medicine 9(1), 1-13
12 Rupali Patil et al.
Chang P, Chen C. (1995) Cytotoxic antileukemic
anthraquinones from Morinda umbellate include
alizarin-1-methyl ether, alizarin, manjistin methyl
ester and 2-hydroxy-anthraquinone-3-aldehyde. Chin.
Phar. J. 47, 347-353.
Chopra RN, Nayar SL, Chopra IC. (1957) In Glossary
of Indian Medicinal Plants, CSIR, New Delhi, India.
Dosseh C, Tessier AM. (1981) Nouvelles quinines des
raciness de Rubia cordifolia Linn. III. Planta med. 43,
360.
Gilani AH, Janbaz KH, Zaman M, Lateef A, Suria A,
Ahmed HR.(1994) Possible presence of calcium
channel blocker(s) in Rubia cordifolia : an indigenous
medicinal plant J. Pak. Med. Asso. 44, 82-85.
Gilani AH, Janbaz KH. (1995) Effect of Rubia cordifolia
extract on acetaminophen and CCl4-induced
hepatotoxicity. Phytother. Res. 9, 372-375.
Gupta PP, Srimal RC, Verma N, Tandon JS. (1999)
Biological Activity of Rubia cordifolia and Isolation
of an Active Principle. Pharm. Biol. 37, 46-49.
Halpern M. (2004) Cancer Part-III: Ayurvedic manageme nt,
California college of Ayurveda.
Ho LK, Don MJ, Chen HC, Yeh SF, Chen JM. (1996)
Inhibition of Hepatitis B Surface Antigen Secretion
on Human Hepatoma Cells. Components from
Rubia cordifolia. J. Nat. Prod. 59, 330-333.
Ho LK, Yub HJ, Hob CT, Don MJ. (2001) Synthesis of
naturally occurring Rubilactone, Mollugin and
Dihydromollugin of Rubia cordifolia. J. Chin. Chem.
Soc. 48, 77-79.
Itokawa H, Qiao YF, Takeya K, Itaka Y. (1989) New
triterpinoids from Rubia cordifolia var. pratensis
(Rubiaceae). Chem. Pharm. Bull. 37, 1670.
Itokawa H, Qiao YF, Takeya K, Itaka Y. (1990) Arborane
type triterpinoids from Rubia cordifolia var. pratensis,
and R. onchotrica. Chem. Pharm. Bull. 38, 1435.
Jain A, Basal E. (2003) Inhibition of Propionibacterium
acnes-induced mediators of inflammation by Indian
herbs. Phytomedicine 10, 34-38.
Jha MK. (1992) The folk veterinary system of Bihar- a
research survey. NDDB, Anand, Gujarat, India.
Joharapurkar AA, Zambad SP, Wanjari MM, Umathe
SN. (2003) In vivo evaluation of antioxidant activity
of alcoholic extract of Rubia cordifolia Linn and its
influence on ethanol-induced immunosuppression.
Indian J. Pharmacol. 35, 232-236.
Kasture VS, Deshmukh VK, Chopde CT. (2000)
Anticonvulsant and behavioral actions of triterpenes
isolated from Rubia cordifolia Linn. Indian J. Exp. Biol.
38, 675-680.
Kirtikar KR, Basu BD. (1980) Indian Medicinal Plants.
Vol II. 2nd edition. International Book Distributors,
Dehradun, p. 1305-1307.
Koyama J, Ogura T, Tagahara K, Konoshima T, Kozuka
M. (1992) Two naphthaquinones from Rubia cordifolia.
Phytochemistry 31, 2907-2908.
Majima H, Tsukagoshi S, Furue H, Suminaga M,
Sakamoto K, Wakabayashi R, Kishino S, Niitani H,
Murata A, Genma A. (1993) Phase I Study of RA-
700. Gan To Kagaku Ryoho. 20, 67-78.
Morita H, Yamamiya T, Takeya K, Itokawa H. (1992)
New antitumour bicyclic hexapeptides, RA-XI, -XII,
-XIII and –XIV from Rubia cordifolia. Chem. Pharm.
Bull. 40, 1352-1354.
Morita H, Yamamiya T, Takeya K. (1993) Conformational
Recognition of RA – XII by 80S ribosomes: a different
line broadening study in 1H NMR spectroscopy.
Chem. Pharm. Bull. 41, 781.
Nadkarni KM. (1976) Indian Materia Medica, Vol. 1
(PDF) Rubia cordifolia: a review. Available from: https://www.researchgate.net/publication/244943682_Rubia_cordifolia_a_review
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