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96 vegetable capsules of the organic Ayurvedic plants--Apamarga (erythrina suberosa), Guduchi, Amalaki, Astragulus and Bhringaraj.
The following study shows the use of Apamarga (Erythrina suberosa stem bark) for anemia and leukemia.
“In this study, the apoptosis-inducing effect of an alcoholic extract from Erythrina suberosa stem bark (ESB) was investigated using human promyelocytic leukemia HL60 cells. Cell viability was estimated by MTT assay. We found that the ESB inhibited cell proliferation in a dose- and time-dependent manner. A series of well-documented morphological changes, such as cell shrinkage, condensation of nuclear chromatin, and nuclear fragmentation, were observed by fluorescence microscopy. The gold standard scanning electron micrographs showed apoptotic bodies and formation of blebs. Cell cycle analysis showed a significant increase in Sub G(0) population of cells above 50 μg/ml. ESB treatment resulted in a dose-dependent increase in annexin V positive cells. Increase in intracellular ROS production up to sixfold was detected in ESB-treated HL60 cells by DCFH-DA assay. Dissipation of mitochondrial membrane potential of intact cells accompanied by increase in cytosolic cytochrome c was observed, which was followed by activation of caspase-9 and -3 but not caspase-8. DNA fragmentation analysis revealed typical ladders as early as 18 h indicative of caspase-3 role in the apoptotic pathway. The overall results suggest that ESB induces mitochondria-mediated intrinsic apoptotic pathway in HL60 cells and might have therapeutic value against human leukemia”.
Apamarga has been extensively used in Ayurveda as an anti-inflammatory agent besides being useful in hemorrhoids, indigestion, cough, asthma, anemia, jaundice .
“Astragalus has been shown to have immunologic benefits by stimulating macrophage and natural killer cell activity and inhibiting T-helper cell type 2 cytokines”. (McCulloch M et al Astragalus-Based Chinese Herbs and Platinum-Based Chemotherapy for Advanced Non–Small-Cell Lung Cancer: Meta-Analysis of Randomized Trials, Journal of Clinical Oncology, Vol 24, No 3 (January 20), 2006: 419-430).
“When the WBC count is low … we have what is medically known as neutropenia. Of course ... Echinacea, bromelain, astragalus, reishi and maitake mushrooms, and various other botanicals may be useful immune-restoring agents in this context”. http://blockmd.com/2010/12/21/conquering-the-number-one-cause-of-cancer-related-deathcancer-and-its-treatments-can-suppress-the-im/
Guduchi or Giloy is a famous Ayurvedic herb, used extensively in treatment for fever, diabetes, urinary tract disorders, anemia, jaundice, asthma, cardiac disorders etc. It is a well known immuno-modulator herb used in the correction of auto-immunity. Botanical name – Tinospora cordifolia
“Amalaki (Emblica officinalis ) and Guduchi (Tinospora cordifolia) help in the nourishment of basic structural body constituents and are supportive for the absorption of iron. Yastimadhu (Glycyrrhiza glabra L.) has Shonita Sthapana (prevent bleeding tendency and normalize hematopoiesis) property. The cumulative effects of all the ingredients leads to the correction of metabolism, iron absorption and improved blood formation, thereby correction of anemia”. http://www.ayujournal.org/article.asp?issn=0974-8520;year=2016;volume=37;issue=3;spage=163;epage=169;aulast=Samal
Bhringaraj. Roots and leaves stimulate the flow of bile into the intestine. The root is used as an emetic and purgative. The leaf juice is used as a liver tonic. This is the main herb for the hair, and cirrhosis. It is believed to prevent aging, maintain and rejuvenate hair, teeth, bones, memory, sight, and hearing. It is a rejuvenative for pitta, kidneys, and liver. The root powder is used in Ayurvedic medicine for hepatitis, enlarged spleen, and skin disorders. http://hepcchallenge.org/wp-content/uploads/2017/09/Appendix_II.pdf
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